CAS No.110-20-3|ACETONE SEMICARBAZONE
CAS No.110-20-3|ACETONE SEMICARBAZONE
CAS No.110-20-3|ACETONE SEMICARBAZONE
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  • CAS No.110-20-3|ACETONE SEMICARBAZONE
  • CAS No.110-20-3|ACETONE SEMICARBAZONE
  • CAS No.110-20-3|ACETONE SEMICARBAZONE

CAS No.110-20-3|ACETONE SEMICARBAZONE

Name:ACETONE SEMICARBAZONE CAS No.110-20-3 EINECS:203-746-7 MF:C4H9N3O MW:115.13 Purity:98% Package: 1kg,5kg,25kg,50kg,100kg Worldwide Delivery

Categories:

Pharmaceutical Intermediates

Product introduction

Introduction and application of  CAS No. 110-20-3 | ACETONE SEMICARBAZONE

 

Synonyms:2-(1-methylethylidene)-hydrazinecarboxamid;

Hydrazinecarboxamide,2-(1-methylethylidene)-;

Acetonesemicarbazon;AcetoneSemecarbazone;

AURORAKA-350;

ACETONESEMICARBAZONE;

(isopropylideneamino)urea;

(propan-2-ylideneamino)urea

 

Specification:

ITEMS

SPECIFICATION

CAS

110-20-3

MF

C4H9N3O

MW

115.13

Melting point

189-190°C

Boiling point

215.41°C

Density

1.1906

Acidity coefficient

12.31±0.46

Color

White to Light yellow

Form

powder to crystal

Storage condition

Keep in dark place,Inert atmosphere,Room temperature

 

Chemical properties:

White powder. Melting point 188℃. Soluble in alcohol, ether and hot water, slightly soluble in water.

 

Usage: This product is used as an intermediate in the production of the drug furantantine.

 

Production method: Use hydrazine hydrate and urea as raw materials, condense them to obtain semicarbazide liquid, and then combine it with acetone to refine the finished product. Mix hydrazine hydrate and urea, heat to 97-104°C, and reflux for 6-7 hours. Cool to 45°C and filter to obtain semicarbazide liquid. Cool the filtrate to 25°C, add acetone, naturally raise the temperature to 50-60°C, and keep it warm for 1 hour. Cool to below 20°C, filter, and dry the filter cake to obtain acetone semicarbazone.

The weight ingredient ratio is: hydrazine hydrate (40%): urea: acetone = 1:0.67:0.56. The yield is 90%. As an intermediate, it appears as white powder with a melting point of 185-189°C. Raw material consumption quota: hydrazine hydrate (40%) 300kg/t, urea (industrial product) 870kg/t, acetone (industrial product) 720kg/t.

 

Package and transportation :

Package: 1kg,5kg,25kg,50kg,100kg

Transportation: by courier/ by air/ by sea

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