CAS No.110-20-3|ACETONE SEMICARBAZONE
Name:ACETONE SEMICARBAZONE CAS No.110-20-3 EINECS:203-746-7 MF:C4H9N3O MW:115.13 Purity:98% Package: 1kg,5kg,25kg,50kg,100kg Worldwide Delivery
Categories:
Pharmaceutical Intermediates
Email:sale06@alfachem.cn
Product introduction
Introduction and application of CAS No. 110-20-3 | ACETONE SEMICARBAZONE
Synonyms:2-(1-methylethylidene)-hydrazinecarboxamid;
Hydrazinecarboxamide,2-(1-methylethylidene)-;
Acetonesemicarbazon;AcetoneSemecarbazone;
AURORAKA-350;
ACETONESEMICARBAZONE;
(isopropylideneamino)urea;
(propan-2-ylideneamino)urea
Specification:
|
ITEMS |
SPECIFICATION |
|
CAS |
110-20-3 |
|
MF |
C4H9N3O |
|
MW |
115.13 |
|
Melting point |
189-190°C |
|
Boiling point |
215.41°C |
|
Density |
1.1906 |
|
Acidity coefficient |
12.31±0.46 |
|
Color |
White to Light yellow |
|
Form |
powder to crystal |
|
Storage condition |
Keep in dark place,Inert atmosphere,Room temperature |
Chemical properties:
White powder. Melting point 188℃. Soluble in alcohol, ether and hot water, slightly soluble in water.
Usage: This product is used as an intermediate in the production of the drug furantantine.
Production method: Use hydrazine hydrate and urea as raw materials, condense them to obtain semicarbazide liquid, and then combine it with acetone to refine the finished product. Mix hydrazine hydrate and urea, heat to 97-104°C, and reflux for 6-7 hours. Cool to 45°C and filter to obtain semicarbazide liquid. Cool the filtrate to 25°C, add acetone, naturally raise the temperature to 50-60°C, and keep it warm for 1 hour. Cool to below 20°C, filter, and dry the filter cake to obtain acetone semicarbazone.
The weight ingredient ratio is: hydrazine hydrate (40%): urea: acetone = 1:0.67:0.56. The yield is 90%. As an intermediate, it appears as white powder with a melting point of 185-189°C. Raw material consumption quota: hydrazine hydrate (40%) 300kg/t, urea (industrial product) 870kg/t, acetone (industrial product) 720kg/t.
Package and transportation :
Package: 1kg,5kg,25kg,50kg,100kg
Transportation: by courier/ by air/ by sea
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